Putting holes in someone does no good if those holes doesn't stop them from shooting you or a loved one while they are still able. Sure a shot to the brain with a 22 LR will do the job but are you capable of making that shot when the guy pulls a knife of a gun on you. I subject you do a little more research before you feel protected by that 22 LR even the 22 mag is questionable. I have many of each and am a dam good shot with them. I can take the buttons off your shirt at self defense range but sure as heck wouldn't carry one if my life might depend on it. I don't feel real comfortable carrying my S&W 380 Bodyguard but there are times it is my only carry gun that will fit in my gym shorts pocket. The 38 Special used to be what law enforcement carried then they seen the need to move up to better calibers when they came came available. The object to to neutralize the threat and as quick as possible. You also don't want to over pernitrate as you are responsible for killing those good people standing behind the bad guy. Other wise I would be carrying my 44 Mag. Another good thing to remember just be cause it was a good shoot and you are not being charged you maybe going to civil court and the bad guys family my want to live in your house. I could say a lot more about this subject as I have done a lot of research into carrying for self defense and have the test equipment to test different calibers and loads. I load and shoot 9 different calibers and know a little bit but probably said enough. I just don't want to see one of my brothers or sisters in this Slingshot family to die because they though they had enough gun. One last thing go and shoot that thing often.
it is a very interesting subject - - the capability of a gun to kill vs using it for self defense can be very different things
It is rather well known that many professional killers will use a 22 with a suppressor and they kill very efficiently with one or two shots to the head - - obviously this tells you that 22 can be very deadly
now having said this does not mean the 22 is necessary a good choice for self defense where you might need stop a very angry person, on speed or pcp who is very intent on killing - - here that same deadly 22 might just make the bad guy even madder and he certainly is not going to be sitting still waiting for you to do a double tap to his skull
just making holes that were not there before could actually make a person more dangerous than they already were - - and the fact they might bleed out and die 10 - 20 minutes later won't really matter much.
frankly if I wanted a tiny pocket gun for self defense I think I would get one of the little 2 shot 45 caliber derringers -